This course serves as the foundational course in caring for adults with health alterations from a holistic perspective. This unit of study concentrates on adults experiencing cardiovascular, respiratory, gastrointestinal, endocrine and related oncological alterations. Concepts of pathophysiology, diagnostics and treatments including pharmacotherapeutics, are integrated throughout the course. Components of Professionalism (competency, legal, ethical, political and economic issues) and Critical Thinking are incorporated throughout this course to enable students to integrate theory and practice.